2-乙酰胺基-2-脱氧-D-半乳糖

N-Acetyl-D-galactosamine
N-乙酰-D-半乳糖胺;N-乙酰基-D-氨基半乳糖;2-乙酰氨基-D-半乳糖;2-乙酰胺基-2-脱氧-D-半乳糖;N-乙酰-D-半乳糖胺水合物;2-氨基-2-脱氧-D-半乳糖盐酸盐;2-乙酰氨基-2-脫氧-D-半乳糖;N-Acetyl-D-galactosamine Hydrate N-乙酰-D-半乳糖胺水合物;N-乙酰-D-氨基半乳糖;N-乙酰基-D-半乳糖胺;三(1,1,1,3,3,3-六氟异丙氧基)硼氢化钠;2-乙酰氨基-2-脱氧-D-吡喃半乳糖;N-乙酰-D-2-氨基半乳糖;N-乙酰-D-半乳糖胺,水合;N-乙酰-D-牛乳糖胺;N-乙酰氨基半乳糖;N-乙酰基软骨糖胺;N-乙酰-d-半乳胺;N-乙酰-D-软骨糖胺;N-乙酰-D-水解乳糖胺
14215-68-0
C8H15NO6
221.21
品牌 商品编号 指标/纯度/参数 包装规格 目录价 您的价格 库存 数量 购物车
TargetMol TG-T5885-1mg 99.92% 1mg ¥108.00 登录可见优惠价格 In stock
TargetMol TG-T5885-5mg 99.92% 5mg ¥198.00 登录可见优惠价格 In stock
TargetMol TG-T5885-10mg 99.92% 10mg ¥297.00 登录可见优惠价格 In stock
TargetMol TG-T5885-25mg 99.92% 25mg ¥538.00 登录可见优惠价格 In stock
TargetMol TG-T5885-50mg 99.92% 50mg ¥787.00 登录可见优惠价格 In stock
TargetMol TG-T5885-100mg 99.92% 100mg ¥1130.00 登录可见优惠价格 In stock
TargetMol TG-T5885-200mg 99.92% 200mg ¥1690.00 登录可见优惠价格 In stock
中文名称: 2-乙酰胺基-2-脱氧-D-半乳糖
英文名称: N-Acetyl-D-galactosamine
产品分类: 糖类
CAS号: 14215-68-0
分子式: C8H15NO6
分子量: 221.21
*产品基础信息:
【产品中文名称】2-乙酰胺基-2-脱氧-D-半乳糖;
【产品英文名称】N-Acetyl-D-galactosamine;
【纯度指标】99.92%;
【品牌】TargetMol;
【CAS号】14215-68-0;
【浓度】;


Product Introduction

Bioactivity

名称N-Acetyl-D-galactosamine
描述N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans.
体外活性N-Acetyl-D-galactosamine (GalNAc or D-GalNAc) on the damage induced by SBA on the membrane permeability and tight junction proteins of piglet intestinal epithelium (IPEC-J2) cells. The IPEC-J2 cells were pre-cultured with 0, 0.125 × 10-4 , 0.25 × 10-4 , 0.5 × 10-4 , 1.0 × 10-4 and 2.0 × 10-4 mmol/L GalNAc at different time period (1, 2, 4 and 8 hr) before being exposed to 0.5 mg/ml SBA for 24 hr.Pre-incubation with GalNAc mitigates the mechanical barrier injury as reflected by a significant increase in trans-epithelial electric resistance (TEER) value and a decrease in alkaline phosphatase (ALP) activity in cell culture medium pre-treated with GalNAc before incubation with SBA as both indicate a reduction in cellular membrane permeability. In addition, mRNA levels of the tight junction proteins occludin and claudin-3 were lower in the SBA-treated groups without pre-treatment with GalNAc. The mRNA expression of occludin was reduced by 17.3% and claudin-3 by 42% (p < 0.01). Moreover, the corresponding protein expression levels were lowered by 17.8% and 43.5% (p < 0.05) respectively. However, in the GalNAc pre-treated groups, occludin and claudin-3 mRNAs were reduced by 1.6% (p > 0.05) and 2.7% (p < 0.01), respectively, while the corresponding proteins were reduced by 4.3% and 7.2% (p < 0.05). In conclusion, GalNAc may prevent the effect of SBA on membrane permeability and tight junction proteins on IPEC-J2s.
存储条件Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
溶解度H2O : 250.00 mg/mL (1130.16 mM), Sonication is recommended.
关键字N-Acetyl-D-galactosamine | NAcetylDgalactosamine | N Acetyl D galactosamine
相关产品Formamide | Guanidine hydrochloride | Glycerol | Aceglutamide | Malic acid | DL-Lysine | Sucrose | Nicotinamide riboside malate | Gluconate Calcium | Thymidine | Corn starch | D(+)-Raffinose pentahydrate
相关库Mouse Metabolite Compound Library | Saccharide and Glycoside Natural Product Library | Human Metabolite Library





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